Developing Antimicrobial Surfaces for Silicone Hydrogels
During the past few decades, advances in contact lens and lens care technologies have further contributed to the safety and efficacy of contact lens wear, making contact lenses an option for more patients than ever before. In fact, it is estimated that there are now over 110 million contact lens wearers worldwide. However, despite the improved oxygen transmissibility of silicone hydrogel lenses and the effectiveness of new lens care solutions, some patients still experience microbial contamination of their contact lenses.
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Early Experiences with Antibacterial Silicone Hydrogel Contact Lenses
The Institute for Eye Research has conducted several short term clinical trials testing the safety and efficacy of investigational antibacterial contact lenses. By developing an antibacterial contact lens that prevents bacterial adhesion we are hoping to reduce the occurrence and severity of infection and inflammation caused by various microbes. Two antibacterial compounds that have been assessed, in separate human clinical trials, are fimbrolides and selenium.
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